Overweight and obesity in adults have reached epidemic proportions in the United States, with a particularly noteworthy increasing incidence among children and adolescents. The WHO recognized obesity as a serious chronic disease more than 10 years ago, and current estimates are that 2.5 million individuals globally die from obesity and its complications each year. Treatment and management strategies are complex and involve many healthcare specialty areas. Furthermore, because pharmacological interventions are limited and frequently associated with complications and contraindications, alternative treatment options are being investigated. This review examines contemporary methods of bariatric endotherapy, particularly endoscopically placed devices such as balloons and bags, and gastric restrictive methods including transoral gastroplasty, botulinum toxin and intragastric prostheses.
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